This paper presents a comprehensive Risk-Based Inspection (RBI) study conducted on a Very High Pressure (VHP) system operating at pressures exceeding 6000 psi. The system, comprising complex equipment and piping, is critical to the operation of a large industrial facility. The RBI study aimed to identify potential failure mechanisms, assess the likelihood and consequences of failure, and prioritize inspection and maintenance activities to ensure the integrity and reliability of the system. Using a combination of qualitative and quantitative methods, including API 581 and ASME PCC-3, the study evaluated the system's design, operating conditions, material properties, and historical data to determine the risk of failure for each component. The results identified high-risk components, including weld joints, flanges, and valves, and recommended targeted inspection and maintenance strategies to mitigate potential failures. The study demonstrated the effectiveness of RBI in optimizing inspection and maintenance activities, reducing downtime, and ensuring the safe and reliable operation of VHP systems. The findings and recommendations from this study can be applied to similar VHP systems in various industries, including oil and gas, chemical processing, and power generation.